Walt Lab

 

The Walt lab pioneered the microwell array-based platforms for ultrasensitive biomarker detection and is now working towards new diagnostic approaches and translating them into products that can non-invasively and more accurately diagnose and assess the states of certain forms of cancer, infectious and neurodegenerative diseases. The technique, known as Single Molecule Arrays (Simoa), utilizes a novel digital readout method and can be used to detect proteins, post-translational modifications, microRNAs and biologically relevant small molecules. Most importantly, Simoa has the ability to improve the limit of detection of conventional enzyme-linked immunosorbent assay (ELISA) by 100-1000 fold. This increased sensitivity is critical for early disease diagnostics and for detecting differences between patients and healthy subjects that may be unobservable by other technologies.

 

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