Publications

2017

Long-Term Measurements of Human Inflammatory Cytokines Reveal Complex Baseline Variations between Individuals, Wu, D.; Dinh, T.L.; Bausk, B.P.; Walt, D.R., The American Journal of Pathology, 2017, in press.

Single Molecule Arrays for ultra-sensitive detection of rat cytokines in serum, Cohen, L.; Xie, L.X.; Xylas, M.E.; Walt, D.R., Journal of Immunological Methods, 2017, in press. 

Highly Localized Adaptive Divergence within Supergenes in Atlantic cod (Gadus morhua) within the Gulf of Maine, Barney, B.T.; Munkholm, C.; Walt, D.R.; Palumbi, S.R., BMC Genomics, 2017, 18, 271-284. DOI: 10.1186/s12864-017-3660-3.

“Single Molecule Arrays for Protein and Nucleic Acid Analysis”, Cohen, L.; Walt, D.R. Annual Review of Analytical Chemistry, 2017, 10, 345-363.

“Digital direct detection of microRNAs using Single Molecule Arrays” Cohen, L.; Hartman, M.; Amardey-Wellington, A.; Walt, D.R. Nucleic Acids Research, 2017. DOI 10.1093/nar/gkx542 

“Rapid and Ultrasensitive Single Molecule Detection of Botulinum Neurotoxin Serotype A1 in Human Serum and Urine using Single Molecule Array Method”, Dinh, T.L.; Ngan, K.C.; Shoemaker, C.B.; Walt, D.R. Forensic Toxicology, 2017, 35, 179-184. DOI: 10.1007/s11419-016-0336-7

2016

“Using Antigen-Antibody Binding Kinetics Parameters to Understand Single Molecule Array Immunoassay Performance”, Dinh, T.L.; Ngan, K.C.; Shoemaker, C.B.; Walt, D.R., Analytical Chemistry, 2016, 88, 11335-11339. DOI: 10.1021/acs.analchem.6b03192.

“Personal microbiomes and next-generation sequencing for laboratory-based education”, Hartman, M.; Harrington, K.; Etson, C.; Fierman, M.; Slonim, D.; Walt, D., FEMS Microbiology Letters, 2016, 363(23): fnw266. DOI: 10.1093/femsle/fnw266.

“Protein Counting in Single Cancer Cells”, Schubert, S.M.; Walter, S.R.; Manesse, M.; Walt, D.R., Analytical Chemistry, 2016, 88(5), 2952-2957. DOI: 10.1021/acs.analchem.6b00146.

“Incorporation of SOMAmer® Reagents in Single Molecule Array (Simoa) Assays for Cytokine Detection with Ultra-high Sensitivity”, Wu, D.; Katilius, E.; Olivas, E.; Dumont Milutinovic, M.; Walt, D.R., Analytical Chemistry, 2016, 88(17), 8385-8389. DOI: 10.1021/acs.analchem.6b02451.

2015

“Catalytic kinetics of single gold nanoparticles observed via optical microwell arrays,” Mayer, K.M.; Shnipes, J.; Davis, D.; Walt, D.R. Nanotechnology, 2015, 26, 055704. DOI: 10.1088/0957-4484/26/5/055704.

“Salivary diagnostics using a portable point-of-service platform: A Review”, Khanna, P., Walt, D.R. Clinical Therapeutics, 2015, 37, 498-504. DOI: 10.1016/j.clinthera.2015.02.004. 

“The stoichiometry of the α-complementation reaction of E. coli β-galactosidase as revealed through single-molecule studies”, Mogalisetti, P., Walt, D.R. Biochemistry, 2015, 54, 1583-1588. DOI: 10.1021/bi5015024.

“Single Molecule Arrays (Simoa) for the Ultra-Sensitive Detection of the Host Immune Response to Dengue Infection”, Gaylord, S.; Abdul-Aziz, S.; Walt, D.R., Journal of Clinical Microbiology, 2015, 53, 1722-1724. DOI: 10.1128/JCM.03487-14. PMID: 25694521.

“Fiber-Optic Array Using Molecularly Imprinted Microspheres for Antibiotic Analysis”, Carrasco, S.; Benito-Peña, E.; Walt, D.R.; Moreno-Bondi, M.C., Chemical Science, 2015, 6, 3139-3147. DOI: 10.1039/C5SC00115C.

“Ultra-Sensitive Detection of Ricin Toxin in Multiple Sample Matrices Using Single Domain Antibodies”, Gaylord, S.T.; Goldman, E.R.; Dinh, T.; Anderson, G.P.; Walt, D.R. Analytical Chemistry, 2015, 87, 6570-6577. DOI: 10.1021/acs.analchem.5b00322.

“Ultra-sensitive protein detection via single molecule arrays towards early stage cancer monitoring”, Schubert, S.M.; Arendt, L.M.; Zhou, W.; Baig, S.; Walter, S.R.; Buchsbaum, R.J.; Kuperwasser, C.; Walt, D.R., Scientific Reports, 2015, 5, 11034. DOI: 10.1038/srep11034. PMID: 26052106.

“Single Molecule Array (Simoa) Assay with Optimal Antibody Pairs for Cytokine Detection in Human Serum Samples”, Wu, D.; Dumont Milutinovic, M.; Walt, D.R., Analyst, 2015, 140, 6277-6282. DOI: 10.1039/C5AN01238D.

“Correlations of Salivary Biomarkers with Clinical Assessments in Patients with Cystic Fibrosis”, Nie, S.; Zhang, H.; Mayer, K.M.; Oppenheim, F.G.; Little, F.F.; Greenberg, J.; Uluer, A.Z.; Walt, D.R., PLOS One, 2015, 10(8), e0135237. DOI: 10.1371/journal.pone.0135237. PMCID: PMC4530931.

“Training the Next Generation of Biomedical Investigators in Glycosciences”. Agre, P.; Bertozzi, C.; Bissell, M.J.; Campbell, K.; Cummings, R.; Desai, U.; Estes, M.; Flotte, T.; Fogleman, G.; Gage, F.H.; Ginsburg, D.; Gordon, J.; Hart, G.; Hascall, V.; Kiessling, L.L.; Kornfeld, S.; Lowe, J.B.; Magnani, J.; Mahal, L.; Medzhitov, R.; Roberts, R.J.; Sackstein, R.; Sarkar, R.; Schnaar, R.; Schwartz, N.; Varki, A.; Walt, D.; Weissman, I. National Heart Lung and Blood Institute Working Group Meeting, 15 April 2015, Bethesda, MD. Journal of Clinical Investigation, 2015, 126, 405-408. DOI: 10.1172/JCI85905. PMID: 26829621.

2014

“Salivary Inflammatory Mediator Profiling and Correlation to Clinical Disease Markers in Asthma”, Little FF, Delgado DM, Wexler PJ, Oppenheim FG, Mitchell P, Feldman JA, Walt DR, Peng RD, Matsui EC, PLOS One, 2014, 9(1), e84449. DOI: 10.1371/journal.pone.0084449.

“Observing single enzyme molecules interconvert between activity states upon heating”, Rojek, M.J., Walt, D.R., PLOS One, 2014, 9(1), e86224. DOI: 10.1371/journal.pone.0086224.

“Protein Measurements in Microwells”, Walt, David R., Lab on a Chip, 2014, 14, 3195-3200. DOI: 10.1039/C4LC00277F.

“An Automated Integrated Platform for Rapid and Sensitive Multiplexed Protein Profiling Using Human Saliva Samples”, Nie, S.; Henley, W.H.; Miller, S.E.; Zhang, H.; Mayer, K.M.; Dennis, P.J.; Oblath, E.A.; Alarie, J.P.; Wu, Y.; Oppenheim, F.G.; Little, F.F.; Uluer, A.Z.; Wang, P.; Ramsey, J.M.; Walt, D.R. Lab on a Chip, 2014, 14, 1087-98. DOI: 10.1039/c3lc51303c. PMID: 24448498.

“Advancing the Speed, Sensitivity and Accuracy of Biomolecular Detection using Multi-Length Scale Engineering”, Shana Kelley, Chad Mirkin, David Walt, Rustem Ismagilov, Mehmet Toner, and Edward Sargen, Nature Nanotechnology, 2014, 9, 969-980. DOI: 10.1038/nnano.2014.261.

“Genome-Wide SNP-Genotyping Array to Study the Evolution of the Human Pathogen Vibrio vulnificus Biotype 3”, Nili Raz, Yael Danin-Poleg, Ryan B. Hayman, Yudi Bar-On, Alex Linetsky, Michael Shmoish, Eva Sanjua, Carmen Amaro, David R. Walt, Yechezkel Kashi, PLOS One, 2014, 9(12), e114576. DOI: 10.1371/journal.pone.0114576.

“Disease detection by ultrasensitive quantification of microdosed synthetic urinary biomarkers”, Warren, A.D.; Gaylord, S.T.; Ngan, K.C.; Dumont Milutinovic, M.; Kwong, G.A.; Bhatia, S.N.; Walt, D.R. Journal of the American Chemical Society, 2014, 136(39):13709-13714. DOI: 10.1021/ja505676h. PMID: 25198059.

2013

“Optical Methods for Single Molecule Detection and Analysis”, D. R. Walt, Anal. Chem., 2013, 85 (3), pp 1258–1263. DOI: 10.1021/ac3027178.

“Direct detection of bacterial genomic DNA at subfemtomolar concentrations using single molecule arrays” Song, Linan; Shan, Dandan; Zhao, Mingwei; Pink, Brian; Minnehan, Kaitlin; York, Lyndsey; Gardel, Melissa; Sullivan, Sean; Phillips, Aaron; Hayman, Ryan; Walt, David; Duffy, David. Analytical Chemistry, 2013, 85(3):1932-9. DOI: 10.1021/ac303426b.

“Multiplexed fluorescent microarray for human salivary protein analysis using polymer microspheres and fiber-optic bundles”, Nie, S.; Benito-Peña, E.; Zhang, H.; Wu, Y.; Walt, D.R. Journal of Visualized Experiments, 2013 Oct 10(80). DOI: 10.3791/50726. PMID: 24145242.

“Measuring atomic emission from beacons for long-distance chemical signaling”, LaFratta, C.N.; Pelse, I.; Falla, J.L.; Liu, Y.; Palacios, M.A.; Manesse, M.; Whitesides, G.M.; Walt, D.R. Analytical Chemistry, 2013, 85, 8933-8936. DOI: 10.1021/ac402494s. PMID: 23987667.

“Dynamic microbead arrays for biosensing applications”, David R. Walt; Phillips, Aaron; Hayman, Ryan; Lafratta, Christopher; Manesse, Mael; Palacios, Manuel, Lab Chip, 2013, 13 (11), 2153 – 2160. DOI: 10.1039/c3lc00044c. PMID: 23615790.

“Assessing the Stochastic Intermittency of Single Quantum Dot Luminescence for Robust Quantification of Biomolecules”, Palacios, Manuel; Lacy, Michael; Schubert, Stephanie; Manesse, Mael; Walt, David, Analytical Chemistry, 2013, 85 (14), 6639–6645. DOI: 10.1021/ac4001332.

“Multiplexed Salivary Protein Profiling for Patients with Respiratory Diseases using Fiber-Optic Bundles and Fluorescent Antibody-Based Microarrays”, Nie, Shuai; Benito-Peña, Elena; Zhang, Huaibin; Wu, Yue; Walt, David. Analytical Chemistry, 2013, 85 (19), 9272–9280. DOI: 10.1021/ac4019523.

2012

“Single-Molecule Studies of Restriction Endonuclease Kinetics”, Candice Etson, Francis Wilburn, Thomas Moody, Victoria Fashakin, David R. Walt, Biophysical Journal, Volume 102(3), Supplement 1, 1/31/2012.

“Robust Error Correction in Infofuses,” G. Morrison, S.W. Thomas III, C.N. LaFratta, J. Guo, M.A. Palacios, S. Sounkusale, D.R. Walt, G.M. Whitesides, L. Mahadevan. Proceedings of the Royal Society A, 2/8/2012, 468(2138), 361-367 2011

“Transforming Glycoscience: A Roadmap for the Future”. Committee on Assessing the Importance nd Impact of Glycomics and Glycoscinces; Board on Chemical Sciences and Technology; Board on Life Sciences. National Research Council Report. 2012, Washington, D.C.: The National Academies Press.

“Oil-sealed femtoliter fiber-optic arrays for single molecule analysis”, Zhang H., Nie, S., Etson, C.M., Wang, C.M., D. R. Walt, Lab Chip, 2012, 12, 2229-2239. DOI: 10.1039/c2lc21113k. PMID: 22311152.

2011

“Lessons learned from the introduction of personalized genotyping into a medical school curriculum,” D.R. Walt, A. Kuhlik, S. Epstein, L.A. Demmer, M. Knight, D. Chelmow, M. Rosenblatt, D.W. Bianchi. Genetics IN Medicine, 2011, 13, 1, 63-66.

“Artificial Noses,” S. Stitzel, M.J. Aernecke, D.R. Walt. Annual Review of Biomedical Engineering, 2011, 13, 1-25.

“Single-Cell Time-Resolved Quorum Responses Reveal Dependence on Cell Density and Configuration,” R.D. Whitaker, S. Pember, B.C. Wallace, C.E. Brodley, D.R. Walt. The Journal of Biological Chemistry, 2011, 24, 21623-32.

“Whole Saliva Proteolysis and its Important Impact on Salivary Diagnostics,” K. Thomadaki, E.J. Helmerhorst, N. Tian, X. Sun, W.L. Siqueira, D.R. Walt, F.G. Oppenheim. Journal of Dental Research, 2011, 90, 1135-1330. DOI: 10.1177/0022034511420721. PMID: 21917601.

“InfoBiology by Printed Assays of Microorganism Colonies for Timed and On-Demand Release of Messages,” M.A. Palacios, E. Benito-Pena, M.A. Manesse, A. Mazzeo , C.N. LaFratta , G.M. Whitesides, D.R. Walt. Proceeding of the National Academy of Sciences, 2011, 108(40), 16510-4.

2010

“Detection and Classification of Ignitable Liquid Residues using a Fluorescence-Based Vapor-Sensitive Microsphere Array,” M.J. Aernecke, D.R. Walt. Journal of Forensic Sciences 2010, 55(1), 178-84.

“Synthesis and Biological Testing of Penicillins: An Investigative Approach to the Undergraduate Teaching Laboratory,” R.D. Whitaker, L. Truhlar, D. Yuksel, D.R. Walt, M. Williams. Journal of Chemical Education, 2010, 87(6), pp 634-636.

“Analytical Chemistry on the Femtoliter Scale,” H.H. Gorris, D.R. Walt. Angewandte Chemie, 2010, 49, 3880-3895.

“Note: Toward multiple addressable optical trapping,” A. Faustov, M.R. Webb, D.R. Walt. The Review of Scientific Instruments, 2010, 81(2), 026109.

“Fibre optic microarrays,” D.R. Walt. Chem. Soc. Rev., 2010, 39(1), 38-50.

“Visualizing Fluorescence: Using a Homemade Fluorescence “Microscope” to View Latent Fingerprints on Paper,” C.N. LaFratta, S.P. Huh, A. Mallillin, P. Riviello, D.R. Walt. Journal of Chemical Education, 2010, 87(10), 1105-1107.

“Single-molecule enzyme-linked immunosorbent assay detects serum proteins at subfemtomolar concentrations,” D.M. Rissin, C.W. Kan, T.G. Campbell, S.C. Stuart, D.R. Fournier, L. Song, T. Piech, P.P. Patel, L. Chang, A.J. Rivnak, E.P. Ferrell, J.D. Randall, G.K. Provuncher, D.R. Walt, D.C. Duffy. Nature Biotechnology, 2010, 28, 595-599.

“Bead-based optical fiber arrays for artificial olfaction,” D.R. Walt. Current Opinion in Chemical Biology, 2010, 14(6), 767-770.

“Toward multiple addressable optical trapping,” A.R. Faustov, M.R. Webb, D.R. Walt. Review of Scientific Instruments, 2010, 81(2, Pt. 1), 026109/1-026109/3.

Before 2010

“Personalized Exposure Assessment: Enabling Future Population-Based Environmental Research,” B.K. Weis, D. Balshaw, J. Barr, D. Brown, M. Ellisman, P. Lioy, G. Omenn, J. Potter, M. Smith, L. Sohn, W.A. Suk, S. Sumner, J. Swenberg, D.R. Walt, S. Watkins, C. Thompson, S. Wilson, Environmental Health Perspectives, 2005

“Array-based Binary Analysis for Bacterial Typing,” J.E. Shepard, Y. Danin-Poleg, Y. Kashi, D.R. Walt, Analytical Chemistry, 2005, 77: 319-326.

Editorial: “Electronic Noses: Wake Up and Smell the Coffee,” D.R. Walt, Analytical Chemistry A-Pages, 2005, 77 (3): 45A.

“Fabrication and Optical Characterization of Imaging Fiber-Based Nanoarrays,” J.M. Tam, L. Song, D.R. Walt, Talanta, 2005, 67: 498-502.

“Individual cell migration analysis using fiber-optic bundles,” C.B. DiCesare, I. Biran, D.R. Walt, Analytical and Bioanalytical Chemistry, 2005, 382: 37-43. DOI: 10.1007/s00216-005-3142-3

“Synthesis of Gold-Poly(methyl methacrylate) Core-shell Nanoparticles by Surface-Confined Atom Transfer Radical Polymerization at Elevated Temperature,” T. Mandal, D.R. Walt, Journal of Polymer Science Part A: Polymer Chemistry, 2005, 43: 3631-3642.

“Extending the Longevity of Fluorescence-Based Sensor Arrays Using Adaptive Exposure,” S. Bencic, D.R. Walt, Analytical Chemistry, 2005, 77 (19): 6155-6162.

“Development of a microfluidic platform with an optical imaging microarray capable of attomolar DNA detection,” M. Bowden, L. Song, D.R. Walt, Analytical Chemistry, 2005, 77 (17): 5583-5588.

“Simultaneous Detection of Multiple Biological Warfare Agents in Environmental Samples Using Fiber-Optic Microsphere-Based Arrays,” L. Song, S. Ahn, D.R. Walt, Journal of Emerging Infectious Disease, 2005, 11 (10): 1629-1632.

“Advances in Miniature Analytical Methods for Medical Diagnostics,” D.R. Walt, Science, 2005, 308: 217-219.

“Simultaneously Monitoring Gene Expression Kinetics and Genetic Noise in Single Cells by Optical Well Arrays,” Y. Kuang, I. Biran, D.R. Walt, Analytical Chemistry 2004, 76(21), 6282-6286.

“An Array of Solutions: Fiber arrays contribute to studies of individual cellular behavior and response,” D.R. Walt, SPIE’S oemagazine, 2005: 19-21.

“Monitoring ‘Promiscuous’ Drug Effects on Single Cells of Multiple Cell Types,” Y. Kuang, D.R. Walt, Analytical Biochemistry, 2005, 345: 320-325.

“Optical fiber-based sensors: application to chemical biology,” K.L. Brogan and D.R. Walt, Current Opinion in Chem. Biology, 2005, 9: 494-500.

“Chemistry: Miniature analytical methods for medical diagnostics,” Walt, David R. Science (Washington, DC, United States) 2005, 308(5719), 217-219.

“Detection of Salmonella spp. using microsphere-based, fiber-optic DNA array,” S. Ahn and D.R. Walt, Analytical Chemistry, 2005, 77: 5041-5047

“Miniature Analytical Methods for Medical Diagnostics,” D.R. Walt, Science, 2005, 308: 217-219.

“Detecting biological warfare agents,” L. Song, S. Ahn, D.R. Walt, Emerging Infectious Diseases, 2005, 11 (10): 1629-1632.

“Progress toward the determination of Sr2+ in highly basic solutions using imaging optical fiber sensor arrays,” D.J. Monk, J. Ueberfeld, D.R. Walt, Journal of Materials Chemistry 2005, 15(40), 4361-4366.

“Digital Concentration Readout of Single Enzyme Molecules Using Femtoliter Arrays and Poisson Statistics,”D.M. Rissin, D.R. Walt, Nano Letters, 2006, 6 (3): 520-3.

“Duplexed Sandwich Immunoassays on a Fiber-Optic Microarray,” D.M. Rissin, D.R. Walt, Analytica Chimica Acta, 2006, 564 (1): 34-39.

“Fiber-Optic Microsphere-Based Arrays for Multiplexed Biological Warfare Agent Detection,” L. Song and D.R. Walt, Analytical Chemistry, 2006, 78 (4): 1023-1033.

“Microbead Chemical Switches: An Approach to Detection of Reactive Organophosphate Chemical Warfare Agent Vapors,” S. Bencic-Nagale, D.R. Walt, J. Journal of the American Chemical Society 2006, 128 (15): 5041-5048.

“Digital Readout of Target Binding with Attomole Detection Limits via Enzyme Amplification in Femtoliter Arrays”, D.M. Rissin, D.R. Walt. Journal of the American Chemical Society, 2006, 128 (19): 6286-6287.

“Parallel microparticle manipulation using an imaging fiber-bundle-based optical tweezer array and a digital micromirror device,” J.M. Tam, I. Biran, D.R. Walt, Applied Physics Letters 2006, 89(19), 194101/1-194101/3.

“Fibre optic microarrays for the detection and enumeration of harmful algal bloom species,” D.M. Anderson, D. Kulis, D. Erdner, S. Ahn and D.R. Walt. African Journal of Marine Science 28(2), 2006.

“Fiber-Optic Microarray for Simultaneous Detection of Multiple Harmful Algal Bloom Species,” S. Ahn, D.M. Kulis, D.L. Erdner, D.M. Anderson, D.R. Walt. American Society of Microbiology: AEM 2006, 72 (9): 332-06.

“Phenotypic consequences of promoter-mediated transcriptional noise,”W.J. Blake, G. Balazsi, M.A. Kohanski, F.J. Isaacs, K.F. Murphy, Y. Kuang, C.R. Cantor, D.R. Walt, J.J. Collins. Molecular Cell 2006, 24(6): 853-865.

“Fiber optic array biosensors,” D.R. Walt. BioTechniques 2006, 41(5): 529, 531, 533, 535.

“Fiber-based single cell analysis of reporter gene expression in yeast two-hybrid systems,” R.D. Whitaker, D.R. Walt. Analytical Biochemistry 2007, 360(1): 63-74.

“Optical-fiber bundles,”H.H. Gorris, T.M. Blicharz, D.R. Walt. The FEBS Journal, 2007, 274: 5462-5470.

“Multianalyte Single-Cell Analysis with Multiple Cell Lines Using a Fiber-Optic Array,”R.D. Whitaker, D.R. Walt. Analytical Chemistry 2007, 79 (23): 9045-9053.

“Smells like Bread,” D.R. Walt, Nature Chemical Biology 2007, 3 (6): 306-307.

“Microsensor Arrays for Saliva Diagnostics,”D.R. Walt, T.M. Blicharz, R.B. Hayman, M. Bowden, W.L. Siqueira, E.J. Helmerhorst, N. Grand-Pierre, F.G. Oppenheim, J.S. Bhatia, F.F. Little, J.S. Brody. Annals of the New York Academy of Sciences 2007, 1098 (Oral Based Diagnostics): 389-400.

“Detecting Oxygen consumption in the proximity of Saccharomyces cerevisiae cells using self-assembled fluorescent nanosensors,”Y. Kuang, D.R. Walt. Biotechnology and Bioengineering 2007, 96 (2): 318-25.

“Observing single enzymes at work,”D.R. Walt, H.H. Gorris, D.M. Rissin. Chem. Eng. News, 2007, 85 (44): 8.

“Stochastic inhibitor release and binding from single-enzyme molecules,” H.H. Gorris, D.M. Rissin, and D.R. Walt, PNAS 2007, vol. 104, no.45, pp.17680-17685.

“Very High Density Sensing Arrays,”C.N. LaFratta, D.R. Walt. Chemical Reviews 2008, 108 (2): 614-637.

“Multiplexed Spectroscopic Detections,” D.R. Walt. Annual Review of Analytical Chemistry 2008, 1, 515-547.

“Distinct and Long-Lived Activity States of Single Enzyme Molecules,” D.M. Rissin, H.H. Gorris, D.R. Walt. Journal of the American Chemical Society 2008, 130(15), 5349-5353.

“Use of Colorimetric Test Strips for Monitoring the Effect of Hemodialysis on Salivary Nitrite and Uric Acid in Patients with End-Stage Renal Disease: A Proof Principle,” T.M. Blicharz, D.M. Rissin, M. Bowden, R.B. Hayman, C. DiCesare, J.S. Bhatia, N. Grand-Pierre, W.L. Siqueira, E.J. Helmerhorst, J. Loscalzo, F.G. Oppenheim, and D.R. Walt. Clinical Chemistry 2008, 54:9, 1473-1480.

“Detection of Single-Molecule DNA Hybridization Using Enzymatic Amplification in an Array of Femtoliter-Sized Reaction Vessels,” Z. Li, R.B. Hayman, D.R. Walt. JACS Communications 2008, 130(38), 12622-12623.

“Fiber-optic sensors for biological and chemical agent detection,”M.J. Aernecke, D.R. Walt. Nano and Microsensors for Chemical and Biological Terrorism Surveillance 2008, 98-115.

“Optrode-based fiber optic biosensors (bio-optrode),”I. Biran, X. Yu, D.R. Walt. Optical Biosensors (2nd Edition) 2008, 3-82.

“Measurement science: The engine of chemical biology,”S. Kelley, D.R. Walt. Current Opinion in Chemical Biology 2008, 12(5), 473-474.

“Saliva-based diagnostic technologies: Highlights of the NIDCR’s program,”E. Kousvelari, J.R. McDevitt, D. Malamud, D.T. Wong, D.R. Walt. Salivary Diagnostics, 2008, 111-121.

“Design, Implementation, and Field Testing of a Portable Optical-Fiber Array Vapor Sensor,”M.J. Aernecke, J. Guo, S. Sonkusale, D.R. Walt. Analytical Chemistry, 2009, 81(13), 5281-5290.

“DNA Detection of Ultra-High Density Optical Fiber-Based Nanoarrays,”J.M. Tam, L. Song, D.R. Walt. Biosensors and Bioelectronics, 2009, 24(8), 2488-2493.

“CMOS microelectrode array for electrochemical lab-on-chip applications,”C.N. LaFratta, V. Agarwal, X. Yu, D.R. Walt. IEEE Sensors Journal 2009, 9(6), 609-615.

“Fiber-Optic Microsphere-Based Antibody Array for the Analysis of Inflammatory Cytokines in Saliva,”T.M. Blicharz, W.L. Siqueira, E.J. Helmerhorst, F.G. Oppenheim, P.J. Wexler, F.F. Little, D.R. Walt. Analytical Chemistry, 2009, 81(6), 2106-2114.

“Mechanistic aspects of horseradish peroxidase elucidated through single-molecule studies,”H.H. Gorris, D.R. Walt. Journal of the American Chemical Society, 2009, 131(17), 6277-6282

“Microsphere-Based Rolling Circle Amplification Microarray for the Detection of DNA and Proteins in a Single Assay,” T. Konry, R.B. Hayman, D.R. Walt. Analytical Chemistry, 2009, 81(14), 5777-5782.

“Multiplexed Sandwich Immunoassays Using Electrochemiluminescence Imaging Resolved at the Single Bead Level,”F. Deiss, C.N. LaFratta, M. Symer, T.M. Blicharz, N. Sojic, D.R. Walt. Journal of the American Chemical Society, 2009, 131(17), 6088-6089.

“Temporally Resolved Fluorescence Spectroscopy of a Microarray-Based Vapor Sensing System,”M.J. Aernecke, D.R. Walt. Analytical Chemistry, 2009, 81(14), 5762-5769.

“Intelligent Medical Diagnostics via Molecular Logic,” T. Konry, D.R. Walt. Journal of the American Chemical Society, 2009, 131(37), 13232-13233.

“Chromatically resolved optical microscope (CROMoscope) – a grating-based instrument for spectral imaging,”M.R. Webb, C.N. LaFratta, D.R. Walt. Analytical Chemistry, 2009, 81(17), 7309-7313.

“Ubiquitous Sensors: When Will They Be Here,” D.R. Walt. ACS Nano, 2009, 3(10), 2876-2880.

“Optical-Fiber Arrays for Vapor Sensing,”M.J. Aernecke, D.R. Walt. Sensors and Actuators, B: Chemical 2009, B142(2), 464-469.

“Infochemistry and infofuses for the chemical storage and transmission of coded information,” S.W. Thomas III, R.C. Chiechi, C.N. LaFratta, M.R. Webb, A. Lee, B.J. Wiley, M.T. Zakin, D.R. Walt, G.M. Whitesides. Proceedings of the National Academy of Sciences of the United States of America, 2009, 106(23), 9147-9150.